Article ID Journal Published Year Pages File Type
8320648 DNA Repair 2015 8 Pages PDF
Abstract

- Peripheral human lymphocytes are unable to repair oxidized purines such as 8-oxoG.
- The repair of DNA single-strand breaks is slow as well.
- Activation of lymphocytes causes an induction of repair proteins and restores repair.
- The induction of repair precedes the stimulation of cell proliferation.
- Induction of the repair glycosylase OGG1 is mediated by MAP kinases and NF-YA.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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