Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8320651 | DNA Repair | 2015 | 13 Pages |
Abstract
- Stimulation of DNA synthesis by Dda helicase requires Gp32 ssDNA-binding protein.
- Gp32-Dda protein-protein interactions stimulate Dda helicase and ATPase activities.
- Gp32 strongly inhibits unwinding of inverted replication fork structures by Dda.
- Gp32 controls where Dda may assemble on DNA replication and repair intermediates.
- Gp32 regulation of Dda may be important for the mechanism of replication restart.
Keywords
dsDNAPNAHelicasessDNASSBElectrophoretic mobility shift assaysingle-stranded deoxyribonucleic aciddouble-stranded deoxyribonucleic acidNucleic AcidSDS-PAGESodium dodecyl sulfate polyacrylamide gel electrophoresisRepairRecombinationEMSA یا electrophoretic mobility shift assay ReplicationSingle-stranded DNA binding protein
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Authors
Christian S. Jordan, Scott W. Morrical,