Article ID Journal Published Year Pages File Type
8320806 DNA Repair 2014 6 Pages PDF
Abstract

- A pyrosequencing method was developed to quantify the outcome of lesion bypass by DNA polymerases.
- This quantitative method was analytically validated.
- In basal conditions, the 8-oxodG bypass by FHs 74 Int cell nuclear extract has about 85% fidelity (insertion of dC).
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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