Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8320806 | DNA Repair | 2014 | 6 Pages |
Abstract
- A pyrosequencing method was developed to quantify the outcome of lesion bypass by DNA polymerases.
- This quantitative method was analytically validated.
- In basal conditions, the 8-oxodG bypass by FHs 74 Int cell nuclear extract has about 85% fidelity (insertion of dC).
Keywords
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Biochemistry
Authors
Amandine Nachtergael, Alexandra Belayew, Pierre Duez,