Single molecule approaches to monitor the recognition and resection of double-stranded DNA breaks during homologous recombination

- Review of single-molecule approaches to monitor recognition and resection of a DSB.
- AFM and EM have determined the architecture of SMC-like proteins involved in repair.
- AFM and EM have been used to visualize intermediates of DNA-end resection.
- MT, OT, TPM and fluorescence monitored the dynamics of DNA-end processing proteins.