Article ID Journal Published Year Pages File Type
8320885 DNA Repair 2014 11 Pages PDF
Abstract
While primordial life is thought to have been RNA-based (Cech, Cold Spring Harbor Perspect. Biol. 4 (2012) a006742), all living organisms store genetic information in DNA, which is chemically more stable. Distinctions between the RNA and DNA worlds and our views of “DNA” synthesis continue to evolve as new details emerge on the incorporation, repair and biological effects of ribonucleotides in DNA genomes of organisms from bacteria through humans.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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