Both genetic and dietary factors underlie individual differences in DNA damage levels and DNA repair capacity

Article ID	Journal	Published Year	Pages	File Type
8321021	DNA Repair	2014	8 Pages	PDF

Abstract

We have determined genetic and dietary factors that modulate DNA integrity. We propose that the positive health effect of fruit intake is partially mediated via DNA damage suppression and a simultaneous increase in DNA repair capacity.

Keywords

PBMC FFQ BER NER DNA damage nucleotide excision repair base excision repair Diet Peripheral blood mononuclear cell DNA strand break DNA repair capacity food frequency questionnaire Genetic polymorphisms Single nucleotide polymorphism SNP

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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Both genetic and dietary factors underlie individual differences in DNA damage levels and DNA repair capacity

Authors

Jana Slyskova, Yolanda Lorenzo, Anette Karlsen, Monica H. Carlsen, Vendula Novosadova, Rune Blomhoff, Pavel Vodicka, Andrew R. Collins,