Unraveling the interplay between senescent dermal fibroblasts and cutaneous squamous cell carcinoma cell lines at different stages of tumorigenesis

Article ID	Journal	Published Year	Pages	File Type
8321999	The International Journal of Biochemistry & Cell Biology	2018	46 Pages	PDF

Keywords

CTGF CSCC TLDA UVR TGFB1 IκBα CXCL1 BME ICAM1 SASP FGF2 FCS IGFBP3 GAPDH DMEM NF-κB MMP TaqMan low-density array EGF CCL2 C-C Motif Chemokine Ligand 2 HDF UVB senescence-associated β-galactosidase Ultraviolet radiation interleukin transforming growth factor beta 1 tumor necrosis factor-alpha EMT Young fetal calf serum Sips Conditioned medium epidermal growth factor fibroblast growth factor 2 basal medium Eagle Connective tissue growth factor TNF-α Nuclear factor-kappa B Senescence-associated secretory phenotype human diploid fibroblast matrix metallopeptidase Dulbecco’s modified eagle’s medium Intercellular adhesion molecule 1 Skin Senescence Replicative senescence Stress-induced premature senescence cutaneous squamous cell carcinoma epithelial-to-mesenchymal transition glyceraldehyde-3-phosphate dehydrogenase

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Unraveling the interplay between senescent dermal fibroblasts and cutaneous squamous cell carcinoma cell lines at different stages of tumorigenesis

Authors

Marie Toutfaire, Elise Dumortier, Antoine Fattaccioli, Martine Van Steenbrugge, Charlotte M. Proby, Florence Debacq-Chainiaux,