Article ID Journal Published Year Pages File Type
8322039 The International Journal of Biochemistry & Cell Biology 2018 8 Pages PDF
Abstract
We propose that non-genetic inhibition is the dominant mechanism causing loss of PP2A tumor suppressor function in cancer cells, possibly because these mechanisms do not elicit genomic instability associated with genetic loss of function of specific PP2A subunits.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Non-genomic mechanisms of protein phosphatase 2A (PP2A) regulation in cancer
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