| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8322356 | The International Journal of Biochemistry & Cell Biology | 2016 | 40 Pages |
Abstract
- A protein-protein interaction between EPAS-1/HIF-2 αand PXR was identified.
- EPAS-1 enhanced the activity of PXR signaling pathway via several mechanisms.
- EPAS-1 attenuated the effect of cytotoxic agents of BGC-823 cells.
Keywords
HREAIB1SRC-1Pregnane X receptor (PXR)JNKsPXRRXRHIF-2αCYP3A4Retinoid X receptorARNTHRPPVDFMDRc-Jun N-terminal kinasesMAPKSp1aryl hydrocarbon receptor nuclear translocatorchromatin immunoprecipitationStomach cancerhypoxia response elementSpecificity protein 1Horseradish peroxidasemitogen-activated protein kinasePropidium iodideCHiP
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Authors
Jiuda Zhao, Zhenzhong Bai, Fan Feng, Erlin Song, Feng Du, Junhui Zhao, Guoshuang Shen, Faxiang Ji, Guoyuan Li, Xinfu Ma, Xingyi Hang, Binghe Xu,