| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8322584 | The International Journal of Biochemistry & Cell Biology | 2015 | 10 Pages |
Abstract
- LPLI promotes the osteogenic differentiation.
- Knockdown of TAZ suppresses the effect of LPLI on osteogenic differentiation.
- LPLI increases the protein level and activity of TAZ through Akt/GSK3β pathway.
- TAZ upregulates Cbfa1-dependent transcription under LPLI treatment.
Keywords
OPNnuclear factor of activated T-cells 5myogenic differentiation antigenLPLiNFAT5PAX8transcriptional co-activator with PDZ-binding motifMyoDCbfa1RTKTAZOCNPAX3GSK3βBMP2PI3KDEXCK1PPARγALPAlkaline phosphataseAktOsteopontinOsteocalcinDexamethasonelarge tumor suppressorPhosphatidyl Inositol 3-kinaseLatsbone morphogenetic protein 2casein kinase 1Glycogen synthase kinase 3βreceptor tyrosine kinasesperoxisome proliferator-activated receptor γ
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Jie Feng, Qinyan Sun, Lei Liu, Da Xing,