| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8322665 | The International Journal of Biochemistry & Cell Biology | 2015 | 10 Pages |
Abstract
- GRP78 facilitates cell-ECM adhesion by induce activation of fibronectin-integrin-β1-FAK signaling pathway.
- GRP78 induced cell-cell dissociation and EMT.
- Snail-2 plays the key role in GRP78 mediated adhesion switch and EMT.
- GRP78 promoted the expression and secretion of TGF-β1, and activated downstream TGF-β/Smad signaling pathway.
Keywords
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Authors
Lichao Zhang, Zongwei Li, Yongsheng Fan, Hanqing Li, Zhouyu Li, Yaoping Li,