Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8322698 | The International Journal of Biochemistry & Cell Biology | 2015 | 33 Pages |
Abstract
- We show a developmental isoform switch of COX6A/COX7A in muscle of humans and mice.
- Liver isoforms are present at birth; heart/muscle isoforms increase â¼3 months of age.
- The physiological isoform switch does not explain reversible mitochondrial disease.
- Developmental changes of COX isoforms may modify other mitochondrial diseases.
Keywords
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Biochemistry
Authors
Veronika Boczonadi, Michele Giunta, Maria Lane, Mar Tulinius, Ulrike Schara, Rita Horvath,