Article ID Journal Published Year Pages File Type
8322698 The International Journal of Biochemistry & Cell Biology 2015 33 Pages PDF
Abstract

- We show a developmental isoform switch of COX6A/COX7A in muscle of humans and mice.
- Liver isoforms are present at birth; heart/muscle isoforms increase ∼3 months of age.
- The physiological isoform switch does not explain reversible mitochondrial disease.
- Developmental changes of COX isoforms may modify other mitochondrial diseases.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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