| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8322706 | The International Journal of Biochemistry & Cell Biology | 2015 | 5 Pages |
Abstract
The matricellular protein WISP1 is a member of the CCN protein family. It is induced by WNT1 and is a downstream target of β-catenin. WISP1 is expressed during embryonic development, wound healing and tissue repair. Aberrant WISP1 expression is associated with various pathologies including osteoarthritis, fibrosis and cancer. Its role in tumor progression and clinical outcome makes WISP1 an emerging candidate for the detection and treatment of tumors.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Irem Gurbuz, Ruth Chiquet-Ehrismann,