Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8323242 | The International Journal of Biochemistry & Cell Biology | 2014 | 14 Pages |
Abstract
- We examined if M2 macrophages mediate in a Sema3A-expression strategy of myoblasts.
- M2 cells infiltrate injured muscle predominantly at the early-differentiation phase.
- M2 secrete HGF that promotes chemotactic migration/Sema3A expression of myoblasts.
- Pro-inflammatory macrophages (M1) by contrast, did not show any significant effect.
- Encouraging a spatiotemporal contribution of M2 to regenerative motoneuritogenesis.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Shohei Sakaguchi, Jun-ichi Shono, Takahiro Suzuki, Shoko Sawano, Judy E. Anderson, Mai-Khoi Q. Do, Hideaki Ohtsubo, Wataru Mizunoya, Yusuke Sato, Mako Nakamura, Mitsuhiro Furuse, Koji Yamada, Yoshihide Ikeuchi, Ryuichi Tatsumi,