Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8323347 | The International Journal of Biochemistry & Cell Biology | 2014 | 6 Pages |
Abstract
These results suggest a possible association between inhibition of VEGF-induced mitochondrial biogenesis through Akt pathway by delphinidin and its anti-angiogenic effect, providing a novel mechanism sustaining the beneficial effect of delphinidin against pathologies associated with excessive angiogenesis such as cancers.
Keywords
TFAMERRαTFB2MPGC1αNADH dehydrogenase subunit 5ND5POLGNRF-1FCCPNOSPRCHUVECSMitochondrial DNAdelphinidinmtDNAHuman umbilical vein endothelial cellsNuclear respiratory factor 1mitochondrial transcription factor ANitric oxidenitric oxide synthaseCarbonyl cyanide 4-(trifluoromethoxy) phenylhydrazoneestrogen-related receptor αEstrogen receptor
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Authors
Lucie Duluc, Caroline Jacques, Raffaella Soleti, Ramaroson Andriantsitohaina, Gilles Simard,