| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8323361 | The International Journal of Biochemistry & Cell Biology | 2014 | 11 Pages |
Abstract
- FZD1 regulated PKCδ and its signalling transduction pathway in MDR cancer cells.
- Rottlerin reduced ABCB1 expression and inhibited the MDR drug pumping ability.
- The FZD1 shRNA-knockdown MDR cells reduced viability and drug pump-out ability.
- FZD1 inhibitor curcumin-treated MDR cells significantly reduced cell viability.
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Authors
Tsai-Hsien Hung, Chuan-Mu Chen, Ching-Ping Tseng, Chih-Jie Shen, Hui-Ling Wang, Kong-Bung Choo, Kowit Yu Chong,