| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8323400 | The International Journal of Biochemistry & Cell Biology | 2014 | 7 Pages |
Abstract
- Mitochondria express α7β2, α3β2 and α4β2 nicotinic acetylcholine receptors.
- Mitochondrial nicotinic receptor subtype distribution is tissue-specific.
- All three receptor subtypes are involved in regulating mitochondrial pore formation.
- α7β2 nicotinic receptors stimulate mainly intramitochondrial PI3K/Akt pathway.
- α3β2 and α4β2 nicotinic receptors also inhibit Src- and CaKMII-dependent pathways.
Keywords
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Authors
Olena Lykhmus, Galyna Gergalova, Lyudmyla Koval, Maxim Zhmak, Sergiy Komisarenko, Maryna Skok,