Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8323575 | The International Journal of Biochemistry & Cell Biology | 2014 | 11 Pages |
Abstract
- Impairment by high glucose of insulin-induced glucose uptake is AMPK dependent.
- AMPKα subunits (1 and 2) are both required for insulin induction of glucose uptake.
- Insulin resistance of podocytes is accompanied by increased PTEN protein levels.
- AMPK-PTEN pathway may be involved in regulation of insulin activity in podocytes.
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Authors
Dorota Rogacka, Agnieszka Piwkowska, Irena Audzeyenka, Stefan Angielski, Maciej Jankowski,