| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8323630 | The International Journal of Biochemistry & Cell Biology | 2014 | 8 Pages |
Abstract
We conclude that WASP regulates DCs polarisation for migration and initiation of actin polymerisation downstream of PI3K in nascent podosomes. Subsequently, ILK mediates the accumulation of integrin-associated proteins during podosome maturation and stability for efficient degradation of the subjacent ECM during the invasive migration of DCs.
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Authors
Mercedes Griera, Ester Martin-Villar, Inmaculada Banon-RodrÃguez, Michael P. Blundell, Gareth E. Jones, Ines M. Anton, Adrian J. Thrasher, Manuel Rodriguez-Puyol, Yolanda Calle,