Regulation of muscle protein synthesis and the effects of catabolic states

Article ID	Journal	Published Year	Pages	File Type
8323844	The International Journal of Biochemistry & Cell Biology	2013	11 Pages	PDF

Abstract

This article is part of a Directed Issue entitled: Molecular basis of muscle wasting.

Keywords

PDK1 GSK-3 4E-BP1 AMPK mTORC1 PDCD4 HRI IRES GEF PKR uORF GCN2 eIF4E binding protein 1 RHEB 70 kDa ribosomal protein S6 kinase 1 p70S6K1 TNF Met-tRNAi NF-κB PI3K LPS REDD IGF-1 TSC mTOR 5′-UTR AMP-activated protein kinase eIF Phosphatidylinositol-4,5-bisphosphate 3-kinase Muscle atrophy inflammation insulin-like growth factor-1 ICU intensive care unit mRNA translation Ras homolog enriched in brain internal ribosome entry site Eukaryotic Initiation Factor guanine nucleotide exchange factor tumor necrosis factor nuclear factor kappa-B upstream open reading frame lipopolysaccharide programmed cell death 4 Insulin resistance 5′-untranslated region Heme-regulated inhibitor Double-stranded RNA-dependent protein kinase PERK Tuberous sclerosis complex glycogen synthase kinase-3

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Regulation of muscle protein synthesis and the effects of catabolic states

Authors

Bradley S. Gordon, Andrew R. Kelleher, Scot R. Kimball,