Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease

Article ID	Journal	Published Year	Pages	File Type
8323897	The International Journal of Biochemistry & Cell Biology	2013	12 Pages	PDF

Abstract

This article is part of a Directed Issue entitled: Molecular basis of muscle wasting.

Keywords

MAFbx TLR TGF GSK3β p70S6K IRS-1 IGF-1 PARP 4E-BP1 GRE TWEAK PI-3K FFM ERK REE AMPK mTOR Redd1 Myogenesis MuRF1 NF-κB Muscle atrophy F-box Nedd4 HIF1α Jnk TSC2 tumor necrosis factor-like weak inducer of apoptosis c-Jun N-terminal kinase MAPK Phosphatidylinositol-4,5-bisphosphate 3-kinase Muscle atrophy STAT amino acid Resting energy expenditure insulin-like growth factor-1 insulin receptor substrate-1 interleukin ALS Chronic obstructive pulmonary disease COPD transforming growth factor fat-free mass tumor necrosis factor-alpha Toll-like receptor forkhead Box O Protein synthesis extracellular signal regulated kinase hypoxia inducible factor 1α TNF-α nuclear factor kappa-light-chain-enhancer of activated B cells FoxO Signal transducer and activator of transcription HPA axis Hypothalamic-pituitary-adrenal axis mammalian target of rapamycin Proteolysis C-reactive protein CRP mitogen activated protein kinase adenosine monophosphate-activated protein kinase poly ADP ribose polymerase Glucocorticoid Glycogen synthase kinase 3β glucocorticoid receptor UPS Ubiquitin

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease

Authors

R.C.J. Langen, H.R. Gosker, A.H.V. Remels, A.M.W.J. Schols,