Article ID Journal Published Year Pages File Type
8324378 The International Journal of Biochemistry & Cell Biology 2013 9 Pages PDF
Abstract
► Interleukin-18 (IL-18) increases tyrosinase activity and melanin synthesis. ► IL-18 activates NF-κB. ► IL-18 activates Akt and inhibits PTEN. ► IL-18 up-regulates the expression levels of p70 S6K and Bcl-2. ► IL-18 induces human primary melanocytes migration.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Interleukin-18 augments growth ability of primary human melanocytes by PTEN inactivation through the AKT/NF-κB pathway
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