Article ID Journal Published Year Pages File Type
8324444 The International Journal of Biochemistry & Cell Biology 2013 12 Pages PDF
Abstract
► IL-17 inhibits urokinase type plasminogen activator (uPA) expression in C2C12 myoblasts. ► The inhibition of uPA expression was concomitant with IL-17 inhibition of myogenesis. ► IL-17 inhibits cell migration, in part by decreasing uPA expression. ► IL-17 reduces uPA expression and cell migration by activating p38 MAPK.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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