Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8324506 | The International Journal of Biochemistry & Cell Biology | 2012 | 9 Pages |
Abstract
Doxorubicin (Dox) significantly reduces bone marrow stem cells (BMSCs) while increasing breast cancer stem cells (BCSCs) in tumor-bearing mice; those effects are correlated with the levels of glucosylceramide synthase (GCS), that enzyme regulates ceramide glycosylation and the synthesis of glycosphingolipids (GSLs).
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Authors
Kaustubh N. Bhinge, Vineet Gupta, Salman B. Hosain, Seetharama D. Satyanarayanajois, Sharon A. Meyer, Benny Blaylock, Qian-Jin Zhang, Yong-Yu Liu,