Article ID Journal Published Year Pages File Type
8324506 The International Journal of Biochemistry & Cell Biology 2012 9 Pages PDF
Abstract
Doxorubicin (Dox) significantly reduces bone marrow stem cells (BMSCs) while increasing breast cancer stem cells (BCSCs) in tumor-bearing mice; those effects are correlated with the levels of glucosylceramide synthase (GCS), that enzyme regulates ceramide glycosylation and the synthesis of glycosphingolipids (GSLs).
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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