Article ID Journal Published Year Pages File Type
8324517 The International Journal of Biochemistry & Cell Biology 2012 5 Pages PDF
Abstract
► Effects of E2 on mitochondrial dynamics were studied in breast cancer cells. ► Our results show increase fusion and decrease fission in response to E2. ► Mitochondrial proliferation was high in E2-treated cells. ► OXPHOS complexes protein levels decline in response to treatment. ► E2 affects mitochondria increasing fusion because functionality decreased.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Mitochondrial dynamics is affected by 17β-estradiol in the MCF-7 breast cancer cell line. Effects on fusion and fission related genes
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