| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8325013 | The International Journal of Biochemistry & Cell Biology | 2011 | 8 Pages |
Abstract
⺠Lumican-deficient osteosarcoma cells have increased adhesive capability onto FN. ⺠Endogenous TGF-β2 activity is obligatory for lumicans' effect. ⺠Lumican/TGF-β2 downstream effectors are pSmad 2, integrin β1 and pFAK. ⺠Lumican is proposed to be an endogenous TGF-β2 inhibitor.
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Authors
Dragana Nikitovic, Georgia Chalkiadaki, Aikaterini Berdiaki, John Aggelidakis, Pavlos Katonis, Nikos K. Karamanos, George N. Tzanakakis,