| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8326251 | The International Journal of Biochemistry & Cell Biology | 2009 | 7 Pages |
Abstract
Interestingly, pharmacological and genetic inhibition of Src abrogates the migratory phenotype of endothelial cells silencing HD-PTP. On these bases, and because we have previously demonstrated that HD-PTP binds and dephosphorylates focal adhesion kinase (FAK), another crucial regulator of cell migration, we hypothesize that HD-PTP participates to the regulation of endothelial motility through its interactions with Src and FAK.
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Authors
Massimo Mariotti, Sara Castiglioni, Jose M. Garcia-Manteiga, Laura Beguinot, Jeanette A.M. Maier,