| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8326994 | International Journal of Biological Macromolecules | 2018 | 9 Pages |
Abstract
The results revealed very rapid immobilization of 150 and 200â¯mg of RML on 1â¯g of silica-NH2 and SBA-NH2, respectively, producing 95-100% of immobilization yield. The specific activity and optimum pH of the immobilized preparations and the effect of temperature and co-solvents on their stabilities as well as the reusability of the derivatives were tested. The immobilized preparations were also used as enantioselective catalyst in kinetic resolution of racemic ibuprofen. Among them, Silica-RML showed the best selectivity with 92.2% enantiomeric excess (ee) and E-value of 33.9.
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Authors
Mehdi Mohammadi, Zohreh Habibi, Somayyeh Gandomkar, Maryam Yousefi,