Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8327004 | International Journal of Biological Macromolecules | 2018 | 30 Pages |
Abstract
The release profile of anti-cancer drug “gemcitabine” followed non-Fickian diffusion mechanism and release profile was best fitted in Korsmeyer-Peppas kinetic model of drug release. The hydrogels were found to be non-thrombogenic, non-haemolytic, mucoadhesive and antioxidant in nature. Incorporation of the GO nano-sheets in the composite hydrogel matrix has improved its mechanical and drug delivery properties and also exerted strong influence on the network density and mesh size of the hydrogels.
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Authors
Baljit Singh, Baldev Singh,