Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8331973 | International Journal of Biological Macromolecules | 2015 | 8 Pages |
Abstract
- Aceclofenac-chitosan cocrystals encapsulated SDDS has been developed successfully.
- Dissolution rate of aceclofenac enhanced by cocrystalization with chitosan.
- Developed floating SDDS is capable of controlling the release of drug for extended time.
- In vitro and In vivo performance of the system is good as expected.
- SDDS system is useful to deliver the poorly soluble and gastric irritant drugs.
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Authors
Mani Ganesh, Ung Jin Jeon, Udhumansha Ubaidulla, Pushparaj Hemalatha, Arthanari Saravanakumar, Mei Mei Peng, Hyun Tae Jang,