| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8333060 | International Journal of Biological Macromolecules | 2014 | 10 Pages |
Abstract
Cyto-compatible, 80Â nm sized chitin/PLGA composite nanogels (chit/PLGA-comp NGs) were prepared by regeneration method and characterized. The multifaceted chit/PLGA-comp NGs were surface modified with Au, Fe3O4, CdTe/ZnTe-QDs and umbelliferone, respectively. 185Â nm sized Au-chit/PLGA-comp NGs, 170Â nm sized QD-chit/PLGA-comp-NGs and 160Â nm sized Fe3O4-chit/PLGA-comp-NGs showed RF heating. The QD-chit/PLGA-comp-NGs and 180Â nm sized umb-chit/PLGA-comp-NGs were well uptaken by Escherichia coli, Staphylococcus aureus and Candida albicans. The chit/PLGA-comp NGs could be useful for microbial monitoring and RF application for cancer therapy. The preliminary data showed that multifaceted chit/PLGA-comp-NGs could be useful for hyperthermia for cancer treatment and microbial labelling and imaging.
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Authors
N. Sanoj Rejinold, Raja Biswas, Gopi Chellan, R. Jayakumar,