Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8333926 | International Journal of Biological Macromolecules | 2013 | 7 Pages |
Abstract
⺠Sulfation of chitosan was achieved successfully via a trimethylsilylated precursor. ⺠Highly sulfated chitosan (DS > 2.1) could be obtained under mild reaction conditions. ⺠Degradation of chitosan could be closely related to free hydroxyl groups. ⺠Degradation reduced with increasing of degree of silylation during the reaction. ⺠A high DS (>2.1) was essential for the anticoagulant activity.
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Authors
Jianhong Yang, Kai Luo, Dinglong Li, Shasha Yu, Jun Cai, Lingyun Chen, Yumin Du,