| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8334145 | International Journal of Biological Macromolecules | 2012 | 9 Pages |
Abstract
⺠Chitosan-grafted-PAMAM copolymer was prepared with simple Michael type addition reaction. ⺠Surface charge density increased due to increase in number of primary amine groups. ⺠pDNA complexation ability of chitosan markedly increases after copolymerization. ⺠The novel water soluble copolymers were comparatively of lower toxicity than PEI. ⺠The novel copolymers may be used safely as drug and gene delivery carrier.
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Authors
Kishor Sarkar, P.P. Kundu,