Article ID Journal Published Year Pages File Type
8334250 International Journal of Biological Macromolecules 2012 9 Pages PDF
Abstract
► Binding of isoflavonoid diadzein with human hemoglobin was investigated. ► Spectroscopic, molecular docking and dynamics studies were carried out. ► β-Trp-37 serves as good indicator for the microenvironment of diadzein inside the protein. ► Diadzein does not interfere with the functionality of the heme of hemoglobin. ► Overall secondary structure of the protein remains unchanged in the presence of the drug.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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