| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8334567 | International Journal of Biological Macromolecules | 2012 | 6 Pages |
Abstract
⺠Nine sulfated ophiopogonpolysaccharides (sOPS1-sOPS9) were prepared. ⺠The effects of nine sOPSs on NDV to infect CEF were compared taking OPS as control. ⺠Sulfation modification could significantly enhance the antiviral activity of OPS. ⺠sOPS3 presented best effect and could be used as a component of antiviral drug. ⺠OPS's optimal modification conditions were CSA-Pry ratio at 1:4 reacting 2 h at 60 °C.
Keywords
SPFSOPsCMF-PBSNDVCEFDMF3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideDMSOMTTOPsEagle's minimum essential mediumdegree of sulfationdimethylformamideDimethyl sulfoxidecalcium and magnesium-free phosphate-buffered salineChicken embryo fibroblastMEMMaintenance mediumNewcastle disease virus
Related Topics
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Biochemistry, Genetics and Molecular Biology
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Authors
Jing Zhang, Yuanliang Hu, Deyun Wang, Tao Qin, Cui Liu, Xu Liu, Xin Sheng, Shanshan Chang, Yunpeng Fan, Liwei Guo, The Luong Nguyen,