| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8334797 | International Journal of Biological Macromolecules | 2012 | 8 Pages |
Abstract
⺠We studied the effects of TFE on cardosin A activity and structure. ⺠Low TFE concentrations induce a decrease on stability and a reversible activity loss. ⺠Medium TFE concentrations inactivated cardosin A and lead to an increase on structure complexity. ⺠MD simulation show significant local alterations on cardosin A flexibility.
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Biochemistry
Authors
Ana Sofia Fraga, Ana Cristina Esteves, Nuno Micaelo, Pedro F. Cruz, Rui M.M. Brito, Margaret Nutley, Alan Cooper, Marlene M.T. Barros, Euclides M.V. Pires,