| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8335286 | International Journal of Biological Macromolecules | 2012 | 11 Pages |
Abstract
⺠Anti-amyloidogenic and disruptive effects of two salen derivatives, EUK-8 and EUK-134. ⺠The 3D structure determination of the molecular associates between lysozyme and the compounds. ⺠The interaction of aromatic rings of the compounds with the hydrophobic region of lysozyme. ⺠The higher efficiency of EUK-134 to either disrupt or inhibit the β-sheet structure. ⺠Essential role of hydrophobicity in anti-aggregating and dis-aggregating activities.
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Authors
Seifollah Bahramikia, Razieh Yazdanparast,