| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8337250 | The Journal of Nutritional Biochemistry | 2013 | 8 Pages |
Abstract
All three proanthocyanidin-rich extracts induced a remarkable decrease in the de novo lipid synthesis in HepG2 cells. Moreover, GSPE rat serum metabolites reduced the total percentage of CE, FC and particularly TG; this reduction was significantly higher than that observed in the cells directly treated with GSPE. In conclusion, the bioactivity of the physiological metabolites that are present in the serum of rats after their ingestion of a proanthocyanidin-rich extract was demonstrated in Hep G2 cells.
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Authors
Ligia Guerrero, Maria Margalef, Zara Pons, Mar Quiñones, Lluis Arola, Anna Arola-Arnal, Begoña Muguerza,