Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8337813 | The Journal of Steroid Biochemistry and Molecular Biology | 2018 | 14 Pages |
Abstract
In the last decades, sulfonated steroids evolved from inactive metabolites intended for excretion to highly relevant compounds involved in many physiological processes. Investigations of the impact of sulfonated steroids on the steroid hormone biosynthesis revealed that, on the one hand, these can serve as substrate for steroidogenic cytochromes P450 and, on the other hand, these are able to influence the catalytic properties of these enzymes. In this review the relevance of sulfonated steroids for the steroid hormone biosynthesis will be discussed.
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Authors
J. Neunzig, R Bernhardt,