Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8337896 | The Journal of Steroid Biochemistry and Molecular Biology | 2018 | 11 Pages |
Abstract
This review is organized in sections as follows: I) a brief synopsis of the current state of knowledge regarding estrogen-induced carcinogenesis, II) a review of evidence from clinical and animal-based studies that support a role for GPER in cancer progression, and III) a mechanistic framework describing how GPER-mediated estrogen action may influence the tumor and its microenvironment.
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Authors
Edward J. Filardo,