| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8338828 | The Journal of Steroid Biochemistry and Molecular Biology | 2014 | 8 Pages |
Abstract
Slightly supra-physiological concentrations of 1α,25(OH)2D3 have a moderate anti-proliferative effect on H295R cells. Anti-proliferative effect was due to cell cycle arrest in G1 phase, without inducing apoptosis. The low mRNA expression levels at qRT-PCR as well as the weak immunohistochemical expression of VDR in ACC, suggests a protective role of VDR against malignant adrenocortical growth.
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Authors
Catia Pilon, Riccardo Urbanet, Tracy A. Williams, Takashi Maekawa, Silvia Vettore, Rosa Sirianni, Vincenzo Pezzi, Paolo Mulatero, Ambrogio Fassina, Hironobu Sasano, Francesco Fallo,