Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8338876 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 34 Pages |
Abstract
⺠Treatment of men with finasteride is used for primary prevention of prostate cancer. ⺠Finasteride suppresses serum DHT levels. ⺠Effect of finasteride on DHT precursors/metabolites in men was studied during 1 year. ⺠DHT sulfate (DHT S) and androstanediol glucuronide were suppressed, similar to DHT. ⺠DHT S, a novel metabolite, may serve as an important marker of 5α-reductase inhibition.
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Authors
Frank Z. Stanczyk, Colleen G. Azen, Malcolm C. Pike,