Article ID Journal Published Year Pages File Type
8338876 The Journal of Steroid Biochemistry and Molecular Biology 2013 34 Pages PDF
Abstract
► Treatment of men with finasteride is used for primary prevention of prostate cancer. ► Finasteride suppresses serum DHT levels. ► Effect of finasteride on DHT precursors/metabolites in men was studied during 1 year. ► DHT sulfate (DHT S) and androstanediol glucuronide were suppressed, similar to DHT. ► DHT S, a novel metabolite, may serve as an important marker of 5α-reductase inhibition.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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