| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8338889 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 48 Pages |
Abstract
⺠Genomes of three strains of mycobacteria producing 3,17-diketoandrostanes from phytosterol were sequenced. ⺠Genomes of AD and ADD producers are nearly identical, that of 9-OH-AD producer differs. ⺠Multiple kstD, kshA and kshB genes were found and annotated. ⺠AD and ADD-producing strains differ by a Lys135Ser substitution in Î1 KSTD.
Keywords
ORFsAcetyl-CoA acetyltransferaseBWAChOxAndrost-4-ene-3,17-dioneEnoyl-CoA hydrataseacyl-CoA dehydrogenaseSingle nucleotide substitutionHSDPWMflavin adenine dinucleotideCTABacyl-CoA synthetaseandrosta-1,4-diene-3,17-dioneADDcetyl trimethyl ammonium bromideFADbase pairOpen reading framesPosition weight matrixhydroxysteroid dehydrogenaseSNPcholesterol oxidase
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Authors
E.Yu. Bragin, V.Yu. Shtratnikova, D.V. Dovbnya, M.I. Schelkunov, Yu.A. Pekov, S.G. Malakho, O.V. Egorova, T.V. Ivashina, S.L. Sokolov, V.V. Ashapkin, M.V. Donova,