| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8338895 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 9 Pages |
Abstract
- Aromatized and non-aromatized androgens had different effects breast cancer cells.
- Testosterone (T) induced proliferation in ER+ co-cultured breast cancer cells.
- DHT suppresses proliferation in both ER+ and ERâ co-cultured breast cancer cells.
- Differences can be explained by conversion of T to estradiol (E2) by fibroblasts.
- Non-aromatized androgens may be a new target for breast cancer treatment.
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Authors
Suthat Chottanapund, Majorie B.M. Van Duursen, Panida Navasumrit, Potchanee Hunsonti, Supatchaya Timtavorn, Mathuros Ruchirawat, Martin Van den Berg,