| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8338896 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 9 Pages |
Abstract
Subtypes B and C showed higher replication in PBMC from males and females and were transmitted more efficiently through DC to male and female PBMC compared with other HIV-1 subtypes, HIV-1 Group O and HIV-2. These findings are consistent with increased worldwide prevalence of subtype B and C compared to other subtypes. Sex steroid hormones had variable effect on replication or transmission of different subtypes. These findings suggest that subtype, gender and sex hormones may play a crucial role in the replication and transmission of HIV.
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Authors
Viswanath Ragupathy, Krishnakumar Devadas, Shixing Tang, Owen Wood, Sherwin Lee, Armeta Dastyer, Xue Wang, Andrew Dayton, Indira Hewlett,