Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8339000 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 13 Pages |
Abstract
⺠Phthalate plasticizers are found ubiquitously in the environment and human fluids. ⺠The effects of DEHP are more severe and long lasting when exposures occur during fetal development. ⺠Early in life exposure to DEHP affects male and female offspring reproductive function. ⺠Exposure to DEHP in utero decreases aldosterone levels and blood pressure in the male offspring.
Keywords
TSPOdehydroepiandrosterone22R-HydroxycholesterolTSHzona reticularisDEHPACTHPPARMEHPGnRHDHEASDHEAPNDsex-determining region of the Y chromosomeTDSdi-(2-ethylhexyl) phthalatemono(2-ethylhexyl) phthalateROSAlczona glomerulosaSex-differences2-Ethylhexanoic acidTriiodothyroninethyroxinegestational daypostnatal dayStarTesticular dysgenesis syndromeSryPhthalateEnvironmentendocrine disruptorzona fasciculataadrenocorticotropic hormoneGonadotropin-releasing hormonefollicle-stimulating hormoneluteinizing hormonethyroid stimulating hormoneFSHSteroid hormonesSteroidogenic acute regulatory proteinPVCmisPolyvinyl chlorideReactive oxygen speciesangiotensin receptorPeroxisome proliferator activated receptorMineralocorticoid receptor
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Authors
D.B. Martinez-Arguelles, E. Campioli, M. Culty, B.R. Zirkin, V. Papadopoulos,