| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8339030 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 11 Pages |
Abstract
- We apply a QSAR model and a docking study in a heterogeneous data set of 269 AS.
- The QSAR model for the AS explains structural features of the steroidal backbone.
- Docking procedure predict the association of AS with the human androgen receptor.
- 14 steroids were identified as lead; the best was 7α-methylestr-4-en-3,17-dione.
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Authors
Yoanna MarÃa Alvarez-Ginarte, Luis Alberto Montero-Cabrera, José Manuel GarcÃa-de la Vega, Alberto Bencomo-MartÃnez, Amaury Pupo, Alina Agramonte-Delgado, Yovani Marrero-Ponce, José Alberto Ruiz-GarcÃa, Hans Mikosch,