Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8339036 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 9 Pages |
Abstract
Serum concentrations of metabolites of both estrogens and androgens remain within the normal postmenopausal range following daily intravaginal administration of 6.5Â mg prasterone. As other studies have shown, local formation of sex steroids in peripheral tissues without significant release of E2 or testosterone in the circulation can be achieved with intravaginal prasterone. Thus, prasterone is a promising physiological and attractive solution to treating VVA symptoms.
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Authors
Fernand Labrie, Céline Martel, René Bérubé, Isabelle Côté, Claude Labrie, Leonello Cusan, José-Luis Gomez,