Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8339146 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 5 Pages |
Abstract
⸠Starting from quinic acid two syntheses of the A-ring synthon were achieved. ⸠2-Methylene calcitriol analogs were synthesized by Pd-catalyzed cross-coupling. ⸠Presence of 2-methylene group at C-2 enhances biological activity of calcitriol.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Izabela K. Sibilska, Marcin Szybinski, Rafal R. Sicinski, Lori A. Plum, Hector F. DeLuca,