Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8339174 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 4 Pages |
Abstract
⸠6-Substituted 19-norcalcitriol analogs were synthesized by Suzuki-Miyaura coupling. ⸠Biological activity of 6-substituted 19-nor-1α,25-(OH)2D3 analogs was investigated. ⸠Presence of substituent at C-6 impairs binding affinity of 19-norvitamin D to VDR.
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Authors
Katarzyna Sokolowska, Rafal R. Sicinski, Antonio Mouriño, Lori A. Plum, Hector F. DeLuca,